Can an AI Agent Run Your Mass Spec Pipeline? Benchmarking the PyOpenMS Skill
A reproducible 250-run study of feature detection, adduct grouping, quantification, and identification, run by an AI agent with and without the pyOpenMS skill.
14 min read
Topic
Skills
10 K-Dense articles on Skills — research automation, benchmarks, and case studies from the K-Dense team.
Beyond RDKit: Benchmarking the Rowan Agent Skill Against Experiment
A reproducible study of pKa, logD, tautomers, ADME, and docking run by an AI agent with the Rowan skill, measured against RDKit and experimental ground truth.
9 min readOne Skill, 78 Databases: Why We Didn't Build 78 Skills
One Agent Skill gives a research agent 78 public scientific and economic databases. Here is the design argument, with real token and routing benchmarks.
12 min readIntroducing Science Superpowers: Scientific Discipline for Your Research Agent
Our new open source methodology makes AI research agents pre-register hypotheses, work reproducibly, and verify before they claim. Pre-registration over TDD.
6 min readTowards Smarter Scientific Search: Exa Joins the Scientific Agent Skills Library
Exa is now integrated into K-Dense's Scientific Agent Skills library, bringing neural web search and URL extraction to AI-driven scientific research.
3 min readIntroducing mimeo and 80+ Mimeographs: Clone an Expert's Way of Thinking Into Your Agent
mimeo distills how great minds like Jobs, Buffett, and Wittgenstein reason into a SKILL.md or AGENTS.md your agent can load, with 80+ experts ready today.
10 min readSecurity in the Science Agent Era: What Every Lab Needs to Know Before Installing Skills
Skills are executable research code with a personality. A practical guide to prompt-injection risks, poisoned SKILL.md files, auditing, and version pinning.
17 min readThe Sandboxed AI Scientist: Pairing NVIDIA OpenShell with Scientific Agent Skills
Pair NVIDIA OpenShell's policy-governed runtime with Scientific Agent Skills to run autonomous research agents that are highly capable and genuinely safe.
13 min readGPU-Accelerate Your Science: 58x Average Speedup with a Single Skill
The optimize-for-gpu skill rewrites CPU-bound Python for NVIDIA GPUs across 12 libraries in data science, ML, and simulation, with 58x average speedup.
8 min readAgent Skills: The Final Piece for AI-Powered Scientific Research
Agent Skills close the gap between raw AI intelligence and domain expertise, adding 140 open-source capabilities to AI scientific research workflows.
8 min read
